Funding
UCSF and the National Institutes of Health currently fund our exciting research. Specific projects and funding sources (including past) are listed below.
Anterior Deep Brain Stimulation for Severe Combined Movement Disorders and Spasticity in Children and Young Adults with Cerebral Palsy
- NIH NINDS UH3NS128297
- Apr 1, 2024 - Mar 31, 2029
- Investigated with PI Dr. Marta San Luciano
- The objective of this study is to develop bilateral cerebellar DBS as a therapy for management of cerebral palsy, including characterizing abnormal patterns of cerebellar oscillatory brain activity and identifying imaging markers of therapeutic response.
Multimodal MRI to Predict DBS Motor and Cognitive Outcomes in Parkinson's Disease
- NIH NINDS R01NS130066
- Sep 19, 2022 - Aug 31, 2027
- The objective of this study is to evaluate the usefulness of preoperative, multimodal MRI (fMRI, DTI, QSM) data for predicting motor and cognitive symptom response to deep brain stimulation in patients with Parkinson's disease.
Targeting DBS Therapy to the OCD Network Using fMRI and Intracranial Recordings (Project complete)
- NIH NIMH R21MH130914
- Jul 1, 2022 - Jun 30, 2025
- Co-investigated with Co-PI Dr. Moses Lee
- The objective of this study is to investigate the networks underlying OCD and the mechanism of DBS using fMRI and intracranial recordings.
Publications
- Schoen, D., Deutsch, S., Mehta, J. et al. Boundary complexity of cortical and subcortical areas predicts deep brain stimulation outcomes in Parkinson’s disease. Nat Commun 16, 5590 (2025). https://doi.org/10.1038/s41467-025-60695-4
Slepneva, N., Basich-Pease, G., Reid, L. et al. Therapeutic DBS for OCD suppresses the default mode network. Human Brain Mapping 45, 18 (2024). e70106. https://doi.org/10.1002/hbm.70106
Please refer to Dr. Morrison’s UCSF profile for the most up-to-date list of publications.